更新时间：2022-03-02
CleanCap® Reagent AG (3' OMe) is TriLink’s proprietary co-transcriptional capping reagent for in vitro transcription of 5’ capped mRNA resulting in a Cap 1 structure. CleanCap has shown to provide up…
CleanCap® Reagent AG (3' OMe) is TriLink’s proprietary co-transcriptional capping reagent for in vitro transcription of 5’ capped mRNA resulting in a Cap 1 structure. CleanCap has shown to provide up to 98% capping efficiency1.
CleanCap AG (3' OMe) includes the 5' N7-Methyl-3'-O-Methylguanosine commonly found in mRNA capped using ARCA, whereas CleanCap AG (N-7113) has a naturally occurring 5' N7-Methylguanosine structure.
| Catalog No | N-7413 |
|---|---|
| Purity | ≥95% by AX-HPLC |
| Extinction Coefficient | 30,539 Lmol-1cm-1 at 255 nm |
| Molecular Formula | C33H45N15O24P4 (free acid) |
| Molecular Weight | 1159.60 |
| Salt Form | Na+ |
| Concentration | 100 mM |
| Buffer | H2O |
| Recommended Storage | -20°C or below |
| Other Name(s) | CleanCap®Reagent AG (3' OMe) for co-transcriptional capping of mRNA, m7(3'OMeG)(5')ppp(5')(2'OMeA)pG |
| Application | CRISPR, In vitro Transcription, Recombinases, TALENS, Transposases, Vaccine Development, Zinc Finger Nucleases |
| Backbone | 5'-5'-Triphosphate |
| Base Analog(s) | Adenosine, Guanosine |
| Nucleotide Category | Cap analogs |
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