产品名称:anti-ZBP1, mAb (Zippy-1)

别名:Z-DNA-binding Protein 1; Tumor Stroma and Activated Macrophage Protein DLM-1; DNA-dependent Activator of IFN-regulatory Factors; DAI

产品描述:ZBP1 is an interferon inducible protein that binds to cytoplasmic DNA and plays a role in host defense against tumors and pathogens. ZBP1 is highly expressed in lymphatic tissues including lymph node, leukocytes, tonsil, bone marrow and spleen. ZBP1 is an innate immune sensor of Influenza A virus (IAV). ZBP1 regulates NLRP3 (nucleotide and oligomerization domain, leucine-rich repeat-containing protein family, pyrin domain containing 3) inflammasome activation as well as induction of different types of cell death (apoptosis, necroptosis and pyroptosis) during IAV infection.

反应种属:Human, Mouse

实验应用:ICC, IP, WB

同种型:Mouse IgG2a

免疫原:Recombinant mouse ZBP1 (aa 1-411).

克隆性:Monoclonal

克隆号:Zippy-1

产品浓度:1mg/ml

保存温度:-20°C

运输温度:BI

产品形式:liquid

存储溶液:Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.

有效期:Stable for at least 1 year after receipt when stored at -20°C.

产地:瑞士

生产商:AdipoGen Life Sciences

样本类型:Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.

纯度:1mg/ml

来源:Purified from concentrated hybridoma tissue culture supernatant.

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