产品名称:anti-Polyglutamylation Modification, mAb (GT335)

别名:Polyglutamylated Tubulin; Glutamylated Tubulin; Postranslational Protein Glutamylation

产品描述:Polyglutamylation is a post-translational modification in which glutamate side chains of variable lengths are formed on the modified protein. It is evolutionarily conserved and the most prominent substrate is tubulin, the microtubule (MT) building block. Polyglutamylation has been proposed to be involved in the functional adaptation of MTs, as it occurs within the carboxy-terminal tubulin tails that participate directly in the binding of many structural and motor MT-associated proteins. The recent identification of new substrates of polyglutamylation indicates that this post-translational modification could be a potential regulator of diverse cellular processes and be involved in cell cycle and cell proliferation.

反应种属:All

实验应用:EM, ICC, IHC, IP, WB

同种型:Mouse IgG1kappa

免疫原:Octapeptide EGEGE*EEG, modified by the addition of two glutamyl units onto the fifth E (indicated by an asterisk).

克隆性:Monoclonal

克隆号:GT335

产品浓度:1mg/ml

保存温度:-20°C

运输温度:BI

产品形式:liquid

存储溶液:Liquid. In PBS containing 0.02% sodium azide.

有效期:Stable for at least 1 year after receipt when stored at -20°C.

产地:瑞士

生产商:AdipoGen Life Sciences

样本类型:Liquid. In PBS containing 0.02% sodium azide.

纯度:1mg/ml

来源:Purified from concentrated hybridoma tissue culture supernatant.

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